Automated Recovery of Samples from NGIs
Automated Recovery of Samples from NGIs
The Xelox® Series Next Generation Impactor (NGI) Sample Recovery System is designed to automate sample preparation and recovery from NGI equipment.
Aerosol and Dry Powder inhalers that contain drug, either in a reservoir or as pre-metered dosage, should be subjected to a test designed to measure Aerodynamic Particle Size Distribution (APSD). This should be measured over the entire inhaler contents. For many companies, recovery of drug sample from NGI cup trays is still performed partially or completely manually.
Automating this process can increase throughput, reduce risk of repetitive strain injury for laboratory personnel, reduce variability of results and improved availability. Automated recovery of samples from NGIs is possible with the Xelox® Series NGI Sample Recovery System.
5 sets of dedicated NGI tray positions, rock samples till drug is fully dissolved. Programmable to suit your method, the trays can tilt from 0º up to 60º on each side for a full agitation movement of up to 120º.
Capable of handling 1ml to 55ml solvent volumes. Volumes can be individually set for each tray using our Relovex software. Astech’s in-house designed covers allow samples to be collected whilst minimising evaporation.
Ready for HPLC – custom vial tray holds all your samples ready for analysis. Use the intuitive touchscreen software to select your desired sample volume from 0.5ml to 50ml.
Automating Inhaler NGI testing is possible with the Xelox® 1 Series NGI Sample Recovery System
The Xelox® NGI Sample Recovery System (SRS) can process up to 5 separate NGI trays. The system automates the otherwise manual process of sample dispensing, agitating and recovery from NGI equipment.
The NGI SRS dispenses a pre-metered volume of solvent into each NGI cup tray, using an automated pipette. The tray assembly is then agitated to fully dissolve the drug captured on each NGI cup tray.
Upon completion of the agitation sequence, a small sample of homogenised drug solution is withdrawn, individually from each NGI cup and dispensed into sample vials. The finished vialled samples are then ready for HPLC/UPLC analysis, to determine the amount of drug contained in each sample recovered.
